A woman died and three other people were injured, one a 3-year-old girl, in a crash south of Waihola yesterday.

The crash between a small rental truck and a car happened on State Highway 1 between Milton and Waihola, south of Dunedin, about 3.20pm. The highway was closed for almost six hours after the crash.

Otago Regional Rescue Helicopter chief pilot Graeme Gale says he flew the 3-year-old girl to Dunedin Hospital. A St John spokesman says she had sustained moderate injuries.

The two other people sustained minor to moderate injuries and were taken by ambulance to Dunedin Hospital.